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Book Details :
Published on: 2013-06-14
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Original language: English

The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events.Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology. Environmental pollution by antibiotics and by antibiotic ... Antibiotics are among the most successful drugs used for human therapy. However since they can challenge microbial populations they must be considered as impo Obojnactwo Wikipedia wolna encyklopedia Hermafrodytyzm obojnactwo dwupciowo gynandromorfizm zjawisko wystpowania w ciele jednego osobnika jednoczenie mskich i eskich gruczow ... Denosumab for Prevention of Fractures in Postmenopausal ... Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor-B ligand (RANKL) that blocks its binding to RANK inhibiting the ... The hidden evolutionary relationship between pigs and ... (Phys.org)In the past geneticists focused primarily on the evolution of genes in order to trace the relationships between species. More recently genetic elements ... Distinct Sets of Genetic Alterations in Melanoma NEJM Original Article. Distinct Sets of Genetic Alterations in Melanoma. John A. Curtin Ph.D. Jane Fridlyand Ph.D. Toshiro Kageshita M.D. Hetal N. Patel M.S. Klaus ... Microbes of the Skin The Scientist Magazine Microbes of the Skin. Human skin the barrier between the body and the outside world is home to diverse microorganisms some of which can promote immunity or fight ... Evolution in Color: From Peppered Moths to Walking Sticks ... But the evidence in favor of natural selection on peppered moths continued to accumulate. For one thing Britain and other countries cleaned up their air in the late ...
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